richardson et al 23 2 established scoring algorithms
spitzer et al 30 recommend 2 different algorithms

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decrease>=50% from phase I baseline HDRS-24
mean age=47.7 ± 9.9 active remitters achieved remission after having failed 1.3 ± 0.8
mean age=47.6 ± 12.6 sham remitters failed 2.2 ± 1.3
mean age=48.1 ± 16.6 remitted during phase II after failing 1.4 ± 0.9
mean age=45 ± 14.4 who entered naturalistic follow up met remission criteria after 3

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mean difference=0.48, p=.02, Cohen's d=0.41
mean difference=0.59, p=.00, Cohen's d=0.52
mean difference=0.69, p<.001, Cohen's d=0.59
mean difference=0.37, p<.001, Cohen's d=0.36

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