Can we predict the direction of sudden shifts in symptoms? Transdiagnostic implications from a complex systems perspective on psychopathology

like increasing levels of autocorrelation
time varying vector autoregressive model
novel approach may yield strongly improved personalized estimations

Clinical implications of the proposed ICD-11 PTSD diagnostic criteria

Common genetic contributions to high-risk trauma exposure and self-injurious thoughts and behaviors

n=6265 twins Heath et al. 2001 Knopik et al. 2004
A=0.62 (0.34-0.90) online Supplementary Table S2

Diagnostic accuracy of dopaminergic imaging in prodromal dementia with Lewy bodies

Disrupted rich club organization and structural brain connectome in unmedicated bipolar disorder

consideration of non standard test statistics

b=1000 s/mm2, five non diffusion weighted b0

Does online insomnia treatment reduce depressive symptoms? A randomized controlled trial in individuals with both insomnia and depressive symptoms

Hedges' g=0.98 Trauer et al., 2015 Wu et al., 2015 van Straten et al., 2017
2010 ; (2) previous CBT I; (3) started psychotherapy<6 months ago; (4) pregnancy/breastfeeding; (5) shift work; (6
PHQ-9; range=0-27, Cronbach's alpha=0.94 Spitzer et al., 1999

Effectiveness of psychotherapy for treatment-resistant depression: a meta-analysis and meta-regression

references of earlier systematic reviews

Efficacy of digital CBT for insomnia to reduce depression across demographic groups: a randomized trial

Exercise effects on cognitive functioning in young adults with first-episode psychosis: FitForLife

detection identification 1 card learning 1 back test

Links between psychotic and neurotic symptoms in the general population: an analysis of longitudinal British National Survey data using Directed Acyclic Graphs

Long-term outcomes of acute treatment with cognitive therapy v. interpersonal psychotherapy for adult depression: follow-up of a randomized controlled trial

previously described linear mixed effect model

tailed alpha=0.05 detect an expected 20%
Up Phase 24 m Post treatment BDI II score<10