p (N 2 - N 1) s i 1 m i 1 + ∑ i=1 p (N 2 - N 1) s i 1 m i 2 - m i 1) + ∑ i=1 p (N 2 - N 1) s i 2 - s i 1) m i 1 + ∑ i=1 p (N 2 - N 1) s i 2 - s i 1) m i 2 - m i 1)</disp formula>Method II differs slightly from method I by decomposing (D 2 - D 1
I=∑ i=1 p N 1 s i 2 - s i 1 m i 1 + ∑ i=1 p (N 2 - N 1) s i 2 - s i 1) m i 1</disp formula><disp formula id="pone.0216613.e005
I I=∑ i=1 p N 1 s i 1 m i 2 - m i 1) + ∑ i=1 p N 1 s i 2 - s i 1) m i 2 - m i 1 + ∑ i=1 p (N 2 - N 1) s i 1 m i 2 - m i 1) + ∑ i=1 p (N 2 - N 1) s i 2 - s i 1) m i 2 - m i 1)</disp formula><disp formula id="pone.0216613.e006
I=∑ i=1 p (N 2 - N 1) s i 1 m i 1
pone.0216613.e007">removedGRAPHIC M p=∑ i=1 p (N 2 - N 1) s i 1 m i 1</disp formula><disp formula id="pone.0216613.e008">removedGRAPHIC M s=∑ i=1 p N 1 s i 2 - s i 1) m i 1</disp formula><disp formula id="pone.0216613.e009">removedGRAPHIC M m=∑ i=1 p N 1 s i 1 m i 2 - m i 1)</disp formula><disp formula id="pone.0216613.e010
m=∑ i=1 p (N 2 - N 1) s i 2 - s i 1) m i 2 - m i 1
pone.0216613.e016">removedGRAPHIC M p '=∑ i=1 p (N 1 - N 2) s i 2 m i 2
i=1 p (N 2 - N 1) s i 2 - s i 1) m i 1

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